Across TCGA patient cohorts, DYNC2H1 mutation is significantly associated with the RNA expression of many other genes, with 7,345 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNC2H1-associated genes across cancer lineages are DRG1, CARS1, and CENPO. Each is linked with DYNC2H1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC2H1-to-partner and partner-to-DYNC2H1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC2H1→partner) and Y-score (partner→DYNC2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DRG1 →	+0.264	+1.253	<.001	<.001	3	6
UCEC	CARS1 →	+0.362	+1.283	<.001	<.001	3	6
LUAD	CENPO →	+0.535	+2.117	<.001	<.001	3	6
UCEC	CCDC9 →	+0.208	+1.337	.002	<.001	3	5
LUAD	KPNA2 →	+0.725	+2.070	<.001	.001	3	5
READ	CMTM4 →	+0.644	+3.188	.007	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,345 associations by consensus.

Exploration

DYNC2H1 survival (RNA) · tumor vs normal (RNA) · all DYNC2H1 data types