Across TCGA patient cohorts, DYNC2H1 mutation is significantly associated with the total protein of many other genes, with 91 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNC2H1-associated genes across cancer lineages are 4E-BP1, ASNS, and eIF4E. Each is linked with DYNC2H1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DYNC2H1-to-partner and partner-to-DYNC2H1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC2H1→partner) and Y-score (partner→DYNC2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.271	+2.632	<.001	<.001	3	5
BRCA	ASNS →	+0.321	+3.169	.033	.020	3	4
UCEC	eIF4E →	+0.168	+1.906	<.001	<.001	3	4
STAD	ACC1 →	+0.481	+2.243	.004	.005	3	4
SKCM	Cyclin-B1 →	+0.442	+1.906	.001	.013	3	4
BRCA	FoxM1 →	+0.293	+2.321	.034	.036	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

Exploration

DYNC2H1 survival (RNA) · tumor vs normal (RNA) · all DYNC2H1 data types