DYNC1LI2

Across TCGA patient cohorts, DYNC1LI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,413 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1LI2-associated proteins across cancer lineages are EDC4, PLEKHO2_T311, and PLEKHO2_T364. Each is linked with DYNC1LI2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC1LI2-to-partner and partner-to-DYNC1LI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1LI2 versus EDC4 in HNSC, with a Pearson correlation of 0.21.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1LI2→partner) and Y-score (partner→DYNC1LI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EDC4 →	+0.212	+0.383	<.001	.003	3	6
LUAD	PLEKHO2_T311 →	-0.551	-0.398	<.001	<.001	3	5
GBM	PLEKHO2_T364 →	-0.353	-0.339	.001	.001	3	5
LUAD	PSME2 →	-0.422	-0.426	<.001	<.001	3	5
GBM	PTPRC →	-0.745	-0.551	<.001	<.001	3	5
PDAC	PTPRC_S994 →	-0.660	-0.342	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,413 associations by consensus.

DYNC1LI2 vs EDC4 — HNSC

Explore this scatter interactively →