DYNC1LI2

Across TCGA patient cohorts, DYNC1LI2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,786 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1LI2-associated genes across cancer lineages are HSH2D, PLEK, and CHD9. Each is linked with DYNC1LI2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC1LI2-to-partner and partner-to-DYNC1LI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1LI2 versus HSH2D in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1LI2→partner) and Y-score (partner→DYNC1LI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSH2D →	-1.389	-0.322	<.001	<.001	3	6
HNSC	PLEK →	-0.979	-0.257	.003	<.001	3	5
BRCA	CHD9 →	+0.663	+0.228	<.001	<.001	3	5
UCEC	KNTC1 →	-0.729	-0.238	<.001	<.001	3	5
PDAC	IFI30 →	-0.469	-0.182	.003	.003	3	5
LSCC	C16orf70 →	+0.474	+0.217	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,786 associations by consensus.

DYNC1LI2 vs HSH2D — BRCA

Explore this scatter interactively →