DYNC1LI2

Across TCGA cell cohorts, DYNC1LI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,485 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYNC1LI2-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with DYNC1LI2 in more than 18 cancer types. Because this analysis shows association rather than direction, both DYNC1LI2-to-partner and partner-to-DYNC1LI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by DYNC1LI2-low versus DYNC1LI2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1LI2→partner) and Y-score (partner→DYNC1LI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.096	+0.921	<.001	<.001	3	19
KIDNEY	Promoter clearance during DNA-templated transcription →	+0.139	+0.765	<.001	.001	3	18
KIDNEY	RNA polymerase II promoter clearance →	+0.139	+0.765	<.001	.001	3	18
URINARY_TRACT	Regulation of organelle assembly →	+0.055	+0.803	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.157	+1.318	<.001	<.001	3	18
SOFT_TISSUE	Nucleic acid transport →	+0.086	+0.714	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,485 associations by consensus.

Regulation of mRNA splicing, via spliceosome by DYNC1LI2 expression — SOFT_TISSUE

Explore this box plot interactively →