DYNC1LI1

Across TCGA patient cohorts, DYNC1LI1 mutation is significantly associated with the RNA expression of many other genes, with 1,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNC1LI1-associated genes across cancer lineages are PSAT1P4, PRAMEF34P, and MIR130A. Each is linked with DYNC1LI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DYNC1LI1-to-partner and partner-to-DYNC1LI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by DYNC1LI1-low versus DYNC1LI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1LI1→partner) and Y-score (partner→DYNC1LI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSAT1P4 →	+0.122	+1.853	.005	.006	3	3
LUAD	PRAMEF34P →	+0.014	+7.930	<.001	.008	3	2
BLCA	MIR130A →	+0.711	+4.533	<.001	.005	3	2
UCEC	SNX3P1Y →	+0.088	+4.308	<.001	.003	3	2
SKCM	OR4F14P →	+0.104	+5.097	<.001	.008	3	2
UCEC	RNU6-1318P →	+0.303	+2.773	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,120 associations by consensus.

PSAT1P4 by DYNC1LI1 expression — UCEC

Explore this box plot interactively →