DYNC1I2

Across TCGA patient cohorts, DYNC1I2 RNA expression is significantly associated with the RNA expression of many other genes, with 19,954 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DYNC1I2-associated genes across cancer lineages are KATNAL1, SPIN1, and BIRC2. Each is linked with DYNC1I2 in more than 33 cancer types. Because this analysis shows association rather than direction, both DYNC1I2-to-partner and partner-to-DYNC1I2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1I2 versus KATNAL1 in TGCT, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I2→partner) and Y-score (partner→DYNC1I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	KATNAL1 →	+1.073	+0.769	<.001	<.001	3	34
THYM	SPIN1 →	+1.494	+1.435	<.001	<.001	3	34
UVM	BIRC2 →	+1.476	+1.111	<.001	<.001	3	34
UVM	SLC35F5 →	+1.568	+1.223	<.001	<.001	3	34
KICH	ORC4 →	+1.127	+1.201	<.001	<.001	3	34
UVM	FASTKD2 →	+1.427	+1.263	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,954 associations by consensus.

DYNC1I2 vs KATNAL1 — TGCT

Explore this scatter interactively →