DYNC1I2

Across TCGA patient cohorts, DYNC1I2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,488 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DYNC1I2-associated proteins across cancer lineages are SEC11C, CD38, and PRKRA. Each is linked with DYNC1I2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC1I2-to-partner and partner-to-DYNC1I2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1I2 versus SEC11C in LSCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I2→partner) and Y-score (partner→DYNC1I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEC11C →	-0.959	-0.495	<.001	<.001	3	6
HNSC	CD38 →	-0.751	-0.505	<.001	.008	3	6
OV	PRKRA →	+0.302	+0.344	.003	.003	3	5
CCRCC	CD74 →	-0.406	-0.216	<.001	<.001	3	5
LSCC	CSDE1_S514 →	-0.717	-0.420	<.001	<.001	3	5
CCRCC	EVI2B →	-0.448	-0.300	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,488 associations by consensus.

DYNC1I2 vs SEC11C — LSCC

Explore this scatter interactively →