DYNC1I2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DYNC1I2 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,678 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DYNC1I2-associated proteins across cancer lineages are DYNC1LI2, DYNC1H1, and DYNLRB1. Each is linked with DYNC1I2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DYNC1I2-to-partner and partner-to-DYNC1I2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1I2 versus DYNC1LI2 in BRCA, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I2→partner) and Y-score (partner→DYNC1I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADYNC1LI2 →+0.370+0.254<.001<.001310
GBMDYNC1H1 →+0.307+0.249<.001<.00139
PDACDYNLRB1 →+0.587+0.322<.001<.00139
GBMDYNLT1 →+0.473+0.187<.001<.00139
OVFKBP3 →+0.461+0.245<.001<.00138
PDACGMFB →+0.503+0.264<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,678 associations by consensus.

DYNC1I2 vs DYNC1LI2 — BRCA

Per-sample scatter of DYNC1I2 vs DYNC1LI2 in BRCA (Pearson r = 0.73).

Explore this scatter interactively →

Exploration