DYNC1I2

Across TCGA cell cohorts, DYNC1I2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,380 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible DYNC1I2-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Cytosolic transport, and Regulation of endoplasmic reticulum tubular network organization. Each is linked with DYNC1I2 in more than 13 cancer types. Because this analysis shows association rather than direction, both DYNC1I2-to-partner and partner-to-DYNC1I2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by DYNC1I2-low versus DYNC1I2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I2→partner) and Y-score (partner→DYNC1I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Phosphatidylinositol biosynthetic process →	+0.069	+0.905	<.001	<.001	2	14
BREAST	Cytosolic transport →	+0.057	+0.585	<.001	<.001	3	12
LUNG_SCLC	Regulation of endoplasmic reticulum tubular network organization →	+0.130	+0.827	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Vesicle-mediated transport to the plasma membrane →	+0.054	+0.821	.003	.003	3	11
LIVER	Regulation of angiotensin-activated signaling pathway →	+0.156	+0.867	.001	<.001	3	11
OESOPHAGUS	Regulation of stress-activated protein kinase signaling cascade →	+0.146	+0.883	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,380 associations by consensus.

Phosphatidylinositol biosynthetic process by DYNC1I2 expression — LUNG_SCLC

Explore this box plot interactively →