DYNC1I1

Across TCGA patient cohorts, DYNC1I1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,494 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1I1-associated proteins across cancer lineages are MAP1LC3A, GOLGA2, and MAP1A. Each is linked with DYNC1I1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DYNC1I1-to-partner and partner-to-DYNC1I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1I1 versus MAP1LC3A in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I1→partner) and Y-score (partner→DYNC1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MAP1LC3A →	+0.748	+0.532	<.001	<.001	3	7
BRCA	GOLGA2 →	-0.219	-0.581	<.001	<.001	3	6
GBM	MAP1A →	+0.639	+1.429	<.001	<.001	3	6
COAD	UCHL1 →	+0.985	+0.500	<.001	.002	3	6
LSCC	MAP1B_S1154 →	+1.207	+1.529	<.001	.001	3	5
LSCC	MAP1B_S1378 →	+0.749	+1.183	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,494 associations by consensus.

DYNC1I1 vs MAP1LC3A — BRCA

Explore this scatter interactively →