DYNC1I1

Across TCGA patient cohorts, DYNC1I1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,389 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1I1-associated genes across cancer lineages are LYVE1, NTRK2, and RERGL. Each is linked with DYNC1I1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DYNC1I1-to-partner and partner-to-DYNC1I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1I1 versus LYVE1 in COAD, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1I1→partner) and Y-score (partner→DYNC1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LYVE1 →	+1.480	+0.734	.003	<.001	3	4
LSCC	NTRK2 →	+1.717	+0.289	<.001	<.001	3	4
BRCA	RERGL →	+1.181	+0.281	<.001	.001	3	3
LSCC	BCHE →	+1.314	+0.354	<.001	<.001	3	3
COAD	CASQ2 →	+1.492	+0.592	.008	.002	2	4
GBM	GALNT13 →	+1.663	+0.460	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,389 associations by consensus.

DYNC1I1 vs LYVE1 — COAD

Explore this scatter interactively →