Across TCGA patient cohorts, DYNC1H1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1H1-associated genes across cancer lineages are RDH11, BTBD7, and ERG28. Each is linked with DYNC1H1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DYNC1H1-to-partner and partner-to-DYNC1H1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1H1→partner) and Y-score (partner→DYNC1H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RDH11 →	+0.816	+0.289	<.001	<.001	3	8
HNSC	BTBD7 →	+0.372	+0.174	.001	.002	3	6
HNSC	ERG28 →	+0.649	+0.196	<.001	<.001	3	6
HNSC	EIF5 →	+0.449	+0.166	<.001	.004	2	6
LSCC	CINP →	+0.453	+0.165	<.001	<.001	3	5
LSCC	AKT1 →	+0.577	+0.212	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,126 associations by consensus.

Exploration

DYNC1H1 survival (RNA) · tumor vs normal (RNA) · all DYNC1H1 data types