DYNAP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DYNAP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,116 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DYNAP-associated GO terms across cancer lineages are Skin epidermis development, Keratinocyte differentiation, and Epidermal cell differentiation. Each is linked with DYNAP in more than 9 cancer types. Because this analysis shows association rather than direction, both DYNAP-to-partner and partner-to-DYNAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skin epidermis development grouped by DYNAP-low versus DYNAP-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNAP→partner) and Y-score (partner→DYNAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCASkin epidermis development →+0.040+1.121<.001<.001310
ESCAKeratinocyte differentiation →+0.072+1.749<.001<.001310
ESCAEpidermal cell differentiation →+0.058+1.880<.001<.00139
ESCAProtein localization to adherens junction →+0.059+1.605<.001<.00139
STADProtein nitrosylation →+0.063+0.396<.001.00139
ESCAEstablishment of endothelial intestinal barrier →+0.040+0.910.004.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,116 associations by consensus.

Skin epidermis development by DYNAP expression — ESCA

Box plot of Skin epidermis development in DYNAP-low vs DYNAP-high samples in ESCA.

Explore this box plot interactively →

Exploration