DYM

Across TCGA patient cohorts, DYM RNA expression is significantly associated with the protein abundance of many other proteins, with 14,593 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DYM-associated proteins across cancer lineages are SMAD4, RPRD1A, and NARS1. Each is linked with DYM in more than 8 cancer types. Because this analysis shows association rather than direction, both DYM-to-partner and partner-to-DYM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYM versus SMAD4 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYM→partner) and Y-score (partner→DYM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMAD4 →	+0.320	+0.583	<.001	<.001	3	9
LSCC	RPRD1A →	+0.375	+0.449	<.001	<.001	3	9
OV	NARS1 →	+0.297	+0.356	<.001	.001	3	7
LSCC	TXNL1 →	+0.407	+0.617	<.001	<.001	3	7
LSCC	SMAD2 →	+0.429	+0.586	<.001	<.001	3	6
COAD	ZNF24 →	+0.467	+0.427	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,593 associations by consensus.

DYM vs SMAD4 — LSCC

Explore this scatter interactively →