DYDC2

Across TCGA patient cohorts, DYDC2 mutation is significantly associated with the RNA expression of many other genes, with 465 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYDC2-associated genes across cancer lineages are RN7SL424P, ZFYVE19, and MUS81. Each is linked with DYDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYDC2-to-partner and partner-to-DYDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL424P grouped by DYDC2-low versus DYDC2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYDC2→partner) and Y-score (partner→DYDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL424P →	+0.489	+4.399	<.001	.008	3	2
SKCM	ZFYVE19 →	+0.405	+3.198	.003	.009	3	2
SKCM	MUS81 →	+0.548	+3.748	<.001	<.001	3	2
UCEC	RNU6-1151P →	+0.332	+3.356	<.001	.005	3	2
SKCM	MIR760 →	+0.400	+2.354	.003	.003	3	2
UCEC	SAAL1 →	+0.694	+3.343	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 465 associations by consensus.

RN7SL424P by DYDC2 expression — LUAD

Explore this box plot interactively →