DYDC2

Across TCGA cell cohorts, DYDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,993 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DYDC2-associated GO terms across cancer lineages are Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, Adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Protein localization to cytoplasmic stress granule. Each is linked with DYDC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DYDC2-to-partner and partner-to-DYDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway grouped by DYDC2-low versus DYDC2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYDC2→partner) and Y-score (partner→DYDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.047	-0.642	<.001	.001	3	7
OVARY	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.052	-0.710	<.001	<.001	3	7
BLOOD_Leukemia	Protein localization to cytoplasmic stress granule →	+0.062	+0.307	.004	.004	3	6
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.123	+1.610	<.001	<.001	3	6
OVARY	Phospholipase C-activating G protein-coupled receptor signaling pathway →	-0.044	-0.603	.001	.003	3	6
OVARY	Purine ribonucleoside triphosphate metabolic process →	+0.086	+0.754	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,993 associations by consensus.

Adenylate cyclase-modulating G protein-coupled receptor signaling pathway by DYDC2 expression — OVARY

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