DYDC1

Across TCGA patient cohorts, DYDC1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYDC1-associated genes across cancer lineages are GATA6, Myosin-IIa_pS1943, and PDCD4. Each is linked with DYDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYDC1-to-partner and partner-to-DYDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA6 grouped by DYDC1-low versus DYDC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYDC1→partner) and Y-score (partner→DYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA6 →	-0.200	-2.992	.024	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.268	+3.013	.025	.019	3	1
UCEC	PDCD4 →	-0.727	-3.000	.007	.037	3	1
UCEC	Stathmin →	+0.183	+3.000	.021	.037	3	1
UCEC	Tuberin →	+0.477	+2.817	.002	.036	3	1
UCEC	Caspase-8 →	-0.348	-3.000	.016	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

GATA6 by DYDC1 expression — UCEC

Explore this box plot interactively →