DYDC1

Across TCGA cell cohorts, DYDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 220 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DYDC1-associated GO terms across cancer lineages are Positive regulation of DNA repair, Cytoskeleton-dependent intracellular transport, and Transport along microtubule. Each is linked with DYDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYDC1-to-partner and partner-to-DYDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by DYDC1-low versus DYDC1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYDC1→partner) and Y-score (partner→DYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of DNA repair →	+0.058	+0.444	.001	.006	3	6
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.042	+0.316	.005	.002	3	5
LUNG_SCLC	Transport along microtubule →	+0.057	+0.403	.001	.002	3	4
BLOOD_Leukemia	mRNA transport →	+0.084	+0.077	<.001	.007	3	4
BLOOD_Leukemia	Negative regulation of cell cycle process →	+0.051	+0.074	<.001	.009	3	3
LUNG_SCLC	Nucleic acid catabolic process →	+0.030	+0.273	.007	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 220 associations by consensus.

Positive regulation of DNA repair by DYDC1 expression — LUNG_SCLC

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