DVL3

Across TCGA patient cohorts, DVL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DVL3-associated proteins across cancer lineages are SDF2, TBL1XR1, and FXR1. Each is linked with DVL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DVL3-to-partner and partner-to-DVL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DVL3 versus SDF2 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DVL3→partner) and Y-score (partner→DVL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDF2 →	+0.489	+0.814	<.001	<.001	3	6
LSCC	TBL1XR1 →	+0.415	+0.753	<.001	<.001	3	6
LSCC	FXR1 →	+0.540	+1.087	<.001	<.001	3	6
LSCC	POLR2H →	+0.379	+0.801	<.001	<.001	3	5
HNSC	RBM12B_S280 →	+0.734	+0.672	<.001	<.001	3	5
GBM	PRPF38A →	+0.216	+0.375	.004	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,470 associations by consensus.

DVL3 vs SDF2 — LSCC

Explore this scatter interactively →