DVL2

Across TCGA patient cohorts, DVL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,623 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DVL2-associated proteins across cancer lineages are HDAC2, MSH2, and SNRNP200. Each is linked with DVL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DVL2-to-partner and partner-to-DVL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DVL2 versus HDAC2 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DVL2→partner) and Y-score (partner→DVL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HDAC2 →	+0.367	+0.455	<.001	.005	3	7
LSCC	MSH2 →	+0.632	+0.835	<.001	<.001	3	7
GBM	SNRNP200 →	+0.285	+0.490	<.001	<.001	3	6
GBM	ADNP →	+0.404	+0.415	<.001	<.001	3	6
GBM	EHMT2 →	+0.436	+0.667	<.001	<.001	3	6
GBM	FXR2 →	+0.307	+0.472	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,623 associations by consensus.

DVL2 vs HDAC2 — GBM

Explore this scatter interactively →