DVL1

Across TCGA patient cohorts, DVL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,310 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DVL1-associated proteins across cancer lineages are NUDC, LRRC47, and DFFA. Each is linked with DVL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DVL1-to-partner and partner-to-DVL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DVL1 versus NUDC in COAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DVL1→partner) and Y-score (partner→DVL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NUDC →	+0.289	+0.340	<.001	.003	3	6
OV	LRRC47 →	+0.468	+1.012	<.001	<.001	3	5
LSCC	DFFA →	+0.345	+0.585	<.001	<.001	3	5
PDAC	ENO1_S263 →	+0.714	+0.528	<.001	<.001	3	5
PDAC	ARHGEF16 →	+0.568	+0.642	<.001	<.001	3	4
CCRCC	RASSF5 →	-0.419	-0.532	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,310 associations by consensus.

DVL1 vs NUDC — COAD

Explore this scatter interactively →