Across TCGA pan-cancer cohorts, DUXAP7 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of DUXAP7’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where DUXAP7 RNA is repressed in tumor relative to normal tissue. In most cancer types DUXAP7 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.
UCEC, THCA, and LUSC are the cancer types where DUXAP7 tumor–normal differential expression is most reproducible.