DUXAP11

Across TCGA patient cohorts, DUXAP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,957 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DUXAP11-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Regulation of telomere maintenance in response to DNA damage, and Establishment of epithelial cell apical/basal polarity. Each is linked with DUXAP11 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUXAP11-to-partner and partner-to-DUXAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by DUXAP11-low versus DUXAP11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUXAP11→partner) and Y-score (partner→DUXAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.139	+0.049	<.001	<.001	3	4
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.130	+0.053	<.001	<.001	3	4
STAD	Establishment of epithelial cell apical/basal polarity →	+0.098	+0.069	<.001	.001	3	4
STAD	Myoblast differentiation →	+0.127	+0.050	<.001	<.001	3	4
STAD	Negative regulation of DNA repair →	+0.104	+0.098	<.001	<.001	3	4
STAD	Double-strand break repair via nonhomologous end joining →	+0.129	+0.085	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,957 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by DUXAP11 expression — STAD

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