Across TCGA patient cohorts, DUX4L45 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,025 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DUX4L45-associated GO terms across cancer lineages are Membrane lipid metabolic process, Negative regulation of neuron projection development, and Regulation of DNA repair. Each is linked with DUX4L45 in more than 7 cancer types. Because this analysis shows association rather than direction, both DUX4L45-to-partner and partner-to-DUX4L45 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L45→partner) and Y-score (partner→DUX4L45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Membrane lipid metabolic process →	+0.035	+0.088	<.001	<.001	3	8
KIRP	Negative regulation of neuron projection development →	+0.039	+0.017	<.001	.001	3	8
UCEC	Regulation of DNA repair →	+0.055	+0.033	<.001	<.001	3	8
ESCA	Recombinational repair →	+0.052	+0.052	<.001	.001	3	8
UCEC	Regulation of double-strand break repair →	+0.054	+0.041	<.001	<.001	3	8
UCEC	Protein-DNA complex assembly →	+0.061	+0.017	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,025 associations by consensus.

Exploration

DUX4L45 survival (RNA) · tumor vs normal (RNA) · all DUX4L45 data types