DUX4L4

Across TCGA pan-cancer cohorts, DUX4L4 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated DUX4L4 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher DUX4L4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DUX4L4 expression acts as an unfavorable survival marker.

STAD and ESCA are the cancer types where DUX4L4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	II,III,IV	0.215	0.660	.019	18	view →
ESCA	OS	Tertile	All	0.176	0.680	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DUX4L4–STAD (OS)

Open the STAD breakdown →