Across TCGA pan-cancer cohorts, DUTP8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DUTP8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where DUTP8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DUTP8 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where DUTP8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DUTP8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	+0.062	.023	2	view →
COAD	All	II,III,IV	+0.047	.040	2	view →
THCA	Female	All	−0.024	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: DUTP8 RNA expression & survival · all DUTP8 data types