DUT

Across TCGA patient cohorts, DUT protein abundance is significantly associated with the RNA expression of many other genes, with 11,365 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DUT-associated genes across cancer lineages are EIF3J, OIP5, and KNSTRN. Each is linked with DUT in more than 6 cancer types. Because this analysis shows association rather than direction, both DUT-to-partner and partner-to-DUT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUT versus EIF3J in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUT→partner) and Y-score (partner→DUT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EIF3J →	+0.648	+0.763	<.001	<.001	3	7
LSCC	OIP5 →	+0.802	+0.559	<.001	<.001	3	7
HNSC	KNSTRN →	+0.985	+0.373	<.001	<.001	3	7
LSCC	BUB1B →	+1.058	+0.524	<.001	<.001	3	7
HNSC	CCNB2 →	+1.127	+0.482	<.001	<.001	3	7
HNSC	PCLAF →	+0.843	+0.409	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,365 associations by consensus.

DUT vs EIF3J — OV

Explore this scatter interactively →