DUSP9

Across TCGA pan-cancer cohorts, DUSP9 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DUSP9 data layer compared with 29 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher DUSP9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DUSP9 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and HNSC are the cancer types where DUSP9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.976	0.897	.001	14	view →
CCRCC	OS	Median	III,IV	1.000	0.353	.022	8	view →
HNSC	OS	Quartile	II,III,IV	0.816	0.995	.006	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DUSP9–LSCC (DFS)

Open the LSCC breakdown →