Across TCGA patient cohorts, DUSP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,168 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DUSP8-associated proteins across cancer lineages are TXNIP, SCYL3_S707, and COBLL1_S788. Each is linked with DUSP8 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUSP8-to-partner and partner-to-DUSP8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP8→partner) and Y-score (partner→DUSP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TXNIP →	-0.443	-0.478	<.001	.001	3	4
UCEC	SCYL3_S707 →	+0.617	+0.669	<.001	<.001	3	4
LUAD	COBLL1_S788 →	+0.457	+0.559	.003	<.001	3	4
CCRCC	BIN2_S395 →	-1.036	-0.706	.005	.002	3	4
LSCC	MYEF2 →	+0.841	+0.431	<.001	.001	3	4
GBM	PTPN6 →	-0.448	-0.610	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,168 associations by consensus.

Exploration

DUSP8 survival (RNA) · tumor vs normal (RNA) · all DUSP8 data types