DUSP8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP8 mutation is significantly associated with the RNA expression of many other genes, with 1,954 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP8-associated genes across cancer lineages are LINC00554, RNU6-841P, and RN7SL89P. Each is linked with DUSP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP8-to-partner and partner-to-DUSP8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP8→partner) and Y-score (partner→DUSP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALINC00554 →+0.024+5.540.001.00432
CESCRNU6-841P →+0.433+5.837<.001.00132
COADRN7SL89P →+0.262+6.020.001<.00132
STADMIR124-3 →+0.402+3.976<.001.00132
UCECMIR615 →+0.175+2.054.005.00532
UCECTCERG1L-AS1 →+0.270+2.026<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,954 associations by consensus.

Exploration