Across TCGA cell cohorts, DUSP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,459 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DUSP8-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Protein targeting to ER. Each is linked with DUSP8 in more than 11 cancer types. Because this analysis shows association rather than direction, both DUSP8-to-partner and partner-to-DUSP8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP8→partner) and Y-score (partner→DUSP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Endoplasmic reticulum to cytosol transport →	+0.116	+1.178	.001	.001	3	12
PANCREAS	Retrograde protein transport, ER to cytosol →	+0.116	+1.178	.001	.001	3	12
PANCREAS	Protein targeting to ER →	+0.093	+1.154	<.001	.001	3	12
PANCREAS	Response to endoplasmic reticulum stress →	+0.057	+1.020	<.001	<.001	3	12
BONE	Cytosolic transport →	+0.075	+1.071	.003	.007	3	11
BONE	Golgi to endosome transport →	+0.089	+0.953	.002	.009	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,459 associations by consensus.

Exploration

DUSP8 survival (RNA) · tumor vs normal (RNA) · all DUSP8 data types