DUSP5P2

Across TCGA pan-cancer cohorts, DUSP5P2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of DUSP5P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DUSP5P2 RNA is repressed in tumor relative to normal tissue. In most cancer types DUSP5P2 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KIRP are the cancer types where DUSP5P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DUSP5P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.641	<.001	12	view →
THCA	Male	III,IV	−0.560	<.001	11	view →
KIRP	All	All	−0.490	<.001	9	view →
LUAD	Male	All	+0.309	<.001	9	view →
KICH	Male	All	−0.895	<.001	7	view →
COAD	Male	All	−0.141	.001	4	view →
BRCA	Female	All	+0.068	<.001	4	view →
HNSC	Male	IV	+0.129	.016	2	view →
LIHC	All	All	+0.061	.017	2	view →
LUSC	All	All	+0.045	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

DUSP5P2–KIRC

Open the KIRC breakdown →