DUSP4

Across TCGA patient cohorts, DUSP4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,527 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUSP4-associated genes across cancer lineages are CBX7, RPL3, and SYNGR1. Each is linked with DUSP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP4-to-partner and partner-to-DUSP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP4 versus CBX7 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP4→partner) and Y-score (partner→DUSP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CBX7 →	+0.720	+0.698	<.001	<.001	3	1
BRCA	RPL3 →	+0.413	+0.509	.001	.002	3	1
BRCA	SYNGR1 →	+0.670	+0.522	.004	.001	3	1
BRCA	L3MBTL2 →	+0.373	+0.511	.002	.009	3	1
BRCA	CHADL →	+0.918	+0.872	<.001	<.001	3	1
BRCA	RBM23 →	+0.381	+0.628	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,527 associations by consensus.

DUSP4 vs CBX7 — BRCA

Explore this scatter interactively →