DUSP4

Across TCGA cell cohorts, DUSP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,364 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DUSP4-associated GO terms across cancer lineages are Viral budding, Endoderm development, and Viral budding via host ESCRT complex. Each is linked with DUSP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both DUSP4-to-partner and partner-to-DUSP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral budding grouped by DUSP4-low versus DUSP4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP4→partner) and Y-score (partner→DUSP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Viral budding →	+0.081	+2.118	<.001	.001	3	10
PANCREAS	Endoderm development →	+0.121	+2.269	.006	.002	3	9
BLOOD_Lymphoma	Viral budding via host ESCRT complex →	+0.077	+1.913	<.001	.004	2	10
LUNG_NSCLC_LUAD	Gastrulation →	+0.039	+1.187	.008	.004	3	9
KIDNEY	Negative regulation of transforming growth factor beta receptor signaling pathway →	+0.047	+1.990	.004	.008	3	8
SOFT_TISSUE	Endoderm formation →	+0.155	+2.074	<.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,364 associations by consensus.

Viral budding by DUSP4 expression — OVARY

Explore this box plot interactively →