Across TCGA patient cohorts, DUSP28 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible DUSP28-associated genes across cancer lineages are TMEM132D-AS2, RN7SL66P, and RPS28P1. Each is linked with DUSP28 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP28-to-partner and partner-to-DUSP28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP28→partner) and Y-score (partner→DUSP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TMEM132D-AS2 →	+0.028	+6.444	<.001	.001	3	1
BLCA	RN7SL66P →	+0.163	+5.177	<.001	.007	3	1
BLCA	RPS28P1 →	+0.222	+5.329	.002	.006	3	1
HNSC	RNU6-1052P →	+0.288	+7.954	<.001	.008	3	1
HNSC	KLF17P2 →	+0.104	+7.954	<.001	.008	3	1
HNSC	MIR3169 →	+0.347	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

DUSP28 survival (RNA) · tumor vs normal (RNA) · all DUSP28 data types