DUSP26

Across TCGA patient cohorts, DUSP26 mutation is significantly associated with the RNA expression of many other genes, with 1,927 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP26-associated genes across cancer lineages are RNU6-289P, RNU6-39P, and RN7SKP286. Each is linked with DUSP26 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP26-to-partner and partner-to-DUSP26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-289P grouped by DUSP26-low versus DUSP26-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP26→partner) and Y-score (partner→DUSP26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-289P →	+0.802	+7.741	<.001	.009	3	2
UCEC	RNU6-39P →	+0.259	+1.796	.004	.008	3	2
SKCM	RN7SKP286 →	+0.053	+5.003	<.001	.002	3	2
UCEC	IGHD1-1 →	+0.477	+3.013	<.001	.001	3	2
CESC	UBE2V1P4 →	+0.195	+5.103	<.001	.008	3	2
UCEC	RNU6-1213P →	+0.202	+3.555	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,927 associations by consensus.

RNU6-289P by DUSP26 expression — COAD

Explore this box plot interactively →