DUSP19

Across TCGA cell cohorts, DUSP19 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible DUSP19-associated genes across cancer lineages are GABRA4, KCNA4, and MTRNR2L5. Each is linked with DUSP19 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP19-to-partner and partner-to-DUSP19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRA4 grouped by DUSP19-low versus DUSP19-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP19→partner) and Y-score (partner→DUSP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	GABRA4 →	+0.031	+4.011	.001	.009	3	1
PANCREAS	KCNA4 →	+0.206	+4.786	<.001	.001	3	1
PANCREAS	MTRNR2L5 →	+0.020	+4.614	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
BLOOD_Leukemia	OR4K2 →	+0.042	+5.969	<.001	.001	3	1
BLOOD_Leukemia	H2AP →	+0.101	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GABRA4 by DUSP19 expression — PANCREAS

Explore this box plot interactively →