DUSP16

Across TCGA patient cohorts, DUSP16 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,833 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUSP16-associated proteins across cancer lineages are MYEF2_S17, PHC1_S664, and PLEKHA5. Each is linked with DUSP16 in more than 5 cancer types. Because this analysis shows association rather than direction, both DUSP16-to-partner and partner-to-DUSP16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP16 versus MYEF2_S17 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP16→partner) and Y-score (partner→DUSP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYEF2_S17 →	+0.819	+0.426	<.001	<.001	3	6
HNSC	PHC1_S664 →	+0.695	+0.536	.001	.001	3	5
BRCA	PLEKHA5 →	+0.372	+0.637	<.001	.001	3	5
HNSC	SMC1A →	+0.249	+0.499	<.001	.001	3	5
OV	CMAS →	+0.543	+0.534	<.001	<.001	3	5
BRCA	CDKN1B →	+0.448	+0.647	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,833 associations by consensus.

DUSP16 vs MYEF2_S17 — LSCC

Explore this scatter interactively →