DUSP15

Across TCGA patient cohorts, DUSP15 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP15-associated genes across cancer lineages are MPP, CD8+ T-cells, and CD8+ naive T-cells. Each is linked with DUSP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP15-to-partner and partner-to-DUSP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by DUSP15-low versus DUSP15-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP15→partner) and Y-score (partner→DUSP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.027	+3.403	.010	.035	3	2
UCEC	CD8+ T-cells →	+0.021	+2.430	<.001	.029	3	2
SKCM	CD8+ naive T-cells →	-0.030	-2.302	.043	.036	3	1
SKCM	Smooth muscle →	+0.110	+3.025	.045	.018	3	1
STAD	Eosinophils →	+0.032	+3.201	.024	.030	3	1
UCEC	CD8+ Tem →	+0.004	+4.744	<.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MPP by DUSP15 expression — COAD

Explore this box plot interactively →