DUSP15

Across TCGA cell cohorts, DUSP15 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DUSP15-associated genes across cancer lineages are FMO1, COX6A2, and DEFA4. Each is linked with DUSP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP15-to-partner and partner-to-DUSP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FMO1 grouped by DUSP15-low versus DUSP15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP15→partner) and Y-score (partner→DUSP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FMO1 →	+0.100	+4.099	.003	.001	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	MAGEB10 →	+0.072	+3.345	<.001	.007	3	1
LARGE_INTESTINE	CCER1 →	+0.011	+3.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

FMO1 by DUSP15 expression — LARGE_INTESTINE

Explore this box plot interactively →