DUSP13

Across TCGA cell cohorts, DUSP13 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DUSP13-associated genes across cancer lineages are ANO5, OR4F5, and PHOX2B. Each is linked with DUSP13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP13-to-partner and partner-to-DUSP13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANO5 grouped by DUSP13-low versus DUSP13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP13→partner) and Y-score (partner→DUSP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANO5 →	+0.633	+3.453	.001	.009	3	1
LARGE_INTESTINE	OR4F5 →	+0.024	+3.345	<.001	.007	3	1
BLOOD_Leukemia	PHOX2B →	+0.021	+4.365	<.001	.002	3	1
BLOOD_Leukemia	CLDN8 →	+0.011	+4.556	<.001	<.001	3	1
BLOOD_Leukemia	SLC35G3 →	+0.044	+3.289	<.001	.009	3	1
BLOOD_Leukemia	ADIG →	+0.015	+4.569	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

ANO5 by DUSP13 expression — LARGE_INTESTINE

Explore this box plot interactively →