DUSP11

Across TCGA pan-cancer cohorts, DUSP11 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DUSP11 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher DUSP11 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DUSP11 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

GBM, PDAC, and LSCC are the cancer types where DUSP11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.566	0.977	<.001	16	view →
PDAC	OS	Median	IV	0.472	0.962	.024	6	view →
LSCC	DFS	Tertile	II,III,IV	0.833	0.591	.040	3	view →
LUAD	OS	Quartile	All	0.597	1.000	.035	3	view →
HNSC	DFS	Median	III,IV	0.935	1.000	.035	1	view →
CCRCC	OS	Tertile	II,III,IV	0.750	0.958	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DUSP11–GBM (DFS)

Open the GBM breakdown →