DUSP11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP11 protein abundance is significantly associated with the RNA expression of many other genes, with 11,046 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DUSP11-associated genes across cancer lineages are PNO1, WDR43, and SRPK1. Each is linked with DUSP11 in more than 4 cancer types. Because this analysis shows association rather than direction, both DUSP11-to-partner and partner-to-DUSP11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP11 versus PNO1 in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP11→partner) and Y-score (partner→DUSP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPNO1 →+0.579+0.173.001.00235
LSCCWDR43 →+0.581+0.278<.001<.00135
BRCASRPK1 →+0.622+0.328<.001.00135
LUADKIF14 →+0.932+0.182<.001<.00135
BRCADLGAP5 →+1.443+0.443<.001<.00135
BRCACCNB1 →+1.025+0.404<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,046 associations by consensus.

DUSP11 vs PNO1 — HNSC

Per-sample scatter of DUSP11 vs PNO1 in HNSC (Pearson r = 0.26).

Explore this scatter interactively →

Exploration