DUSP11

Across TCGA cell cohorts, DUSP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,230 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DUSP11-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Maintenance of location in cell, and Maintenance of location. Each is linked with DUSP11 in more than 9 cancer types. Because this analysis shows association rather than direction, both DUSP11-to-partner and partner-to-DUSP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by DUSP11-low versus DUSP11-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP11→partner) and Y-score (partner→DUSP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of protein ubiquitination →	+0.048	+0.541	.004	<.001	3	10
BONE	Maintenance of location in cell →	+0.070	+0.536	.001	.005	3	10
CNS	Maintenance of location →	+0.062	+0.389	<.001	.003	3	9
LUNG_NSCLC_LUSC	Protein localization to condensed chromosome →	+0.097	+0.407	.009	.006	2	10
OVARY	Regulation of DNA damage checkpoint →	+0.082	+0.396	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Monoubiquitinated protein deubiquitination →	+0.100	+0.910	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

Regulation of protein ubiquitination by DUSP11 expression — KIDNEY

Explore this box plot interactively →