DUSP10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP10 protein abundance is significantly associated with the RNA expression of many other genes, with 297 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUSP10-associated genes across cancer lineages are PICK1, CENPM, and PABPC1L. Each is linked with DUSP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP10-to-partner and partner-to-DUSP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP10 versus PICK1 in BRCA, with a Pearson correlation of -0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP10→partner) and Y-score (partner→DUSP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPICK1 →-1.060-0.504.004.00731
BRCACENPM →-2.026-0.643<.001.00931
BRCAPABPC1L →-1.556-0.504.007.00731
BRCARBFA →-0.923-0.495.002.00931
BRCAMPG →-1.432-0.504.007.00731
BRCAELOB →-1.338-0.504.005.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 297 associations by consensus.

DUSP10 vs PICK1 — BRCA

Per-sample scatter of DUSP10 vs PICK1 in BRCA (Pearson r = -0.95).

Explore this scatter interactively →

Exploration