DUSP10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DUSP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,737 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DUSP10-associated GO terms across cancer lineages are Plasma membrane organization, Negative regulation of cytokine production, and Maintenance of protein location. Each is linked with DUSP10 in more than 12 cancer types. Because this analysis shows association rather than direction, both DUSP10-to-partner and partner-to-DUSP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane organization grouped by DUSP10-low versus DUSP10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP10→partner) and Y-score (partner→DUSP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEPlasma membrane organization →+0.143+1.863<.001<.001313
OVARYNegative regulation of cytokine production →+0.053+1.626<.001<.001313
BONEMaintenance of protein location →+0.152+3.097<.001<.001313
BONENegative regulation of immune response →+0.098+2.377<.001<.001313
OESOPHAGUSRegulation of response to cytokine stimulus →+0.070+2.080.003.001313
BONEPositive regulation of protein maturation →+0.200+1.883<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,737 associations by consensus.

Plasma membrane organization by DUSP10 expression — BONE

Box plot of Plasma membrane organization in DUSP10-low vs DUSP10-high samples in BONE.

Explore this box plot interactively →

Exploration