DUSP1

Across TCGA patient cohorts, DUSP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,960 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DUSP1-associated proteins across cancer lineages are LMNA_S423, PRPF38B_S529, and YJU2_S179. Each is linked with DUSP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both DUSP1-to-partner and partner-to-DUSP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP1 versus LMNA_S423 in BRCA, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP1→partner) and Y-score (partner→DUSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LMNA_S423 →	+1.683	+1.492	<.001	<.001	3	9
CCRCC	PRPF38B_S529 →	-0.546	-1.067	<.001	<.001	3	8
LSCC	YJU2_S179 →	+1.149	+1.310	<.001	<.001	3	7
LSCC	MRTFA_S385 →	+0.871	+1.332	<.001	<.001	3	7
GBM	NAA10_S182 →	-0.512	-1.025	<.001	<.001	3	7
LSCC	NELFE_S353 →	-0.689	-1.078	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,960 associations by consensus.

DUSP1 vs LMNA_S423 — BRCA

Explore this scatter interactively →