DUSP1

Across TCGA patient cohorts, DUSP1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,998 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DUSP1-associated genes across cancer lineages are HSPA9, C5orf15, and TRAPPC13. Each is linked with DUSP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP1-to-partner and partner-to-DUSP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP1 versus HSPA9 in LUAD, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP1→partner) and Y-score (partner→DUSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HSPA9 →	-0.547	-0.584	.008	.005	3	2
LUAD	C5orf15 →	-0.552	-0.583	.003	.006	3	2
LUAD	TRAPPC13 →	-0.577	-0.621	<.001	.001	3	2
LUAD	RARS1 →	-0.541	-0.789	<.001	<.001	3	2
LSCC	RAB3GAP1 →	-0.324	-0.361	<.001	.008	3	2
LSCC	LAMTOR2 →	-0.462	-0.443	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,998 associations by consensus.

DUSP1 vs HSPA9 — LUAD

Explore this scatter interactively →