DUS3L

Across TCGA patient cohorts, DUS3L mutation is significantly associated with the RNA expression of many other genes, with 2,943 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUS3L-associated genes across cancer lineages are OR51T1, RNU5A-4P, and GAPDHP56. Each is linked with DUS3L in more than 2 cancer types. Because this analysis shows association rather than direction, both DUS3L-to-partner and partner-to-DUS3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by DUS3L-low versus DUS3L-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUS3L→partner) and Y-score (partner→DUS3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OR51T1 →	+0.038	+4.730	.001	.005	3	3
LUAD	RNU5A-4P →	+0.469	+3.690	<.001	.009	3	3
CESC	GAPDHP56 →	+0.020	+4.247	<.001	.007	3	3
COAD	H2BC2P →	+0.389	+5.332	<.001	.002	3	3
LGG	RNU6-383P →	+0.368	+7.977	<.001	.007	3	2
LGG	AGGF1P4 →	+0.054	+7.977	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

OR51T1 by DUS3L expression — LUAD

Explore this box plot interactively →